28-04-2016, 04:39
I posted this last year, take a look at the diagram in table 2, in specifically the increase in dhea, progesterone, FSH (follicle stimulating hormone-----a pure aromatase imo) testosterone and prolactin, respectively. From the study I believe the bump in libido comes from DHEA (similar to maca), however, the way FG increases E2 (dramatically in month 2) comes from its aromatase capabilities (from multiple pathways I believe), but mostly from FSH.
my interpretation of how FG increases E2 is explained above.
(26-08-2015, 21:41)Lotus Wrote: Influence of a Specialized Trigonella foenum- graecum Seed Extract (Libifem), on Testosterone, Estradiol and Sexual Function in Healthy Menstruating Women, a Randomised Placebo Controlled Study
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The aim of the study was to evaluate the effect of Trigonellafoenum-graecum (fenugreek) seed extract on sex hormones and sexual function in healthy menstruating women who reported low sexual drive. This short term, single site, double blind, randomised, placebo-controlled study was conducted on 80 women, aged 20 to 49 years. Participants were randomised to either an oral dose of a standardised T. foenum-graecum seed extract (libifem) at a dose of 600 mg/day or placebo over two menstrual cycles. Dehydroepiandrosterone sulfate, progesterone, androstenedione, total and free testosterone, estradiol (E2), luteinizing hormone, follicle stimulating hormone, sex hormone binding globulin and cholesterol were measured at baseline and 8 weeks. The individual aspects of sexual function were measured using the Derogatis interview for sexual functioning and female sexual function index self-administered questionnaires. Stress, fatigue and quality of the relationship with partner were also measured using the PSS (Perceived Stress Scale), MFI-20 (Multidimensional Fatigue Inventory) and DAS (Dyadic Adjustment Scale) quality of life measures, respectively. There was a significant increase in free testosterone and E2 in the active group as well as sexual desire and arousal compared with the placebo group. The results indicate that this extract of T. foenum-graecum may be a useful treatment for increasing sexual arousal and desire in women. Copyright © 2015 John Wiley & Sons, Ltd.
https://www.researchgate.net/profile/Lui...-Study.pdf
(27-08-2015, 00:17)Lotus Wrote: Well yeah, but judging from this study FG pretty much upregulates everything, see here:
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Administration of T. foenum-graecum seed extract was also associated with a significant increase in E2 levels. Estradiol stimulates vaginal lubrication and blood flow, affecting a woman’s capacity for sexual arousal and orgasm (Simon, 2011); this supports the significant positive change in sexual arousal observed. Whilst the mechanism of the increase in E2 levels is unclear from the current study, one possibility is due to increased aromatase activity that converts testosterone to E2.
my interpretation of how FG increases E2 is explained above.
so I discontinued that herb.