[Lotus]

I started my NBE program in April by taking 1tsp of ground fenugreek a day and I noticed that my boobs got fuller, especially around the first few weeks of taking it. They haven't increased in cupsize (I'm still a 34B), but they just fill up my bra more. I still continue to take it daily. I feel like my boobs haven't really changed for the past weeks though, they've just stayed as they are, so I want to add more to my program but not sure where to start.

I guess massage is always good, so I'll implement that. I cannot get a Noogleberry because of the ridiculous international shipping cost, so I'm not looking to get any devices any time soon. Buying anything online is also very expensive here, so I feel like I've got limited options. Should I try finding pueraria mirifica? Is it ok to take fenugreek and PM together? I'm just worried about my hormones not being balanced.

What do you recommend I do next?

Femina, women metabolize drugs 20-30% quicker then men. The following human study found FG dramatically increases E2 levels in month 2. The amount used in the study was only 300 mg, suggest women need massive amounts is risky. Stick with FG for a few cycles then evaluate. I wouldn't add PM at this point, (if ever). Work on diet, exercise, massage and balancing hormones during break the next few months. Add lemons (sliced) w/ filtered water 6-8 cups per day, which also inhibit androgens.

Clinical studies indicate that women metabolise drugs which are substrates of CYP3A4 more quickly than men (20–30% increase)4. Analysis has shown around two fold higher levels of CYP3A4 protein in female compared to male tissue samples3,4. http://www.medsafe.govt.nz/profs/PUArticles/March2014DrugMetabolismCytochromeP4503A4.htm

I posted this last year, take a look at the diagram in table 2, in specifically the increase in dhea, progesterone, FSH (follicle stimulating hormone-----a pure aomatase imo) testosterone and prolactin, respectively. From the study I believe the bump in libido comes from DHEA (similar to maca), however, the way FG increases E2 (dramatically in month 2) comes from its aromatase capabilities (from multiple pathways I believe), but mostly from FSH.



Influence of a Specialized Trigonella foenum- graecum Seed Extract (Libifem), on Testosterone, Estradiol and Sexual Function in Healthy Menstruating Women, a Randomised Placebo Controlled Study
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The aim of the study was to evaluate the effect of Trigonellafoenum-graecum (fenugreek) seed extract on sex hormones and sexual function in healthy menstruating women who reported low sexual drive. This short term, single site, double blind, randomised, placebo-controlled study was conducted on 80 women, aged 20 to 49 years. Participants were randomised to either an oral dose of a standardised T. foenum-graecum seed extract (libifem) at a dose of 600 mg/day or placebo over two menstrual cycles. Dehydroepiandrosterone sulfate, progesterone, androstenedione, total and free testosterone, estradiol (E2), luteinizing hormone, follicle stimulating hormone, sex hormone binding globulin and cholesterol were measured at baseline and 8 weeks. The individual aspects of sexual function were measured using the Derogatis interview for sexual functioning and female sexual function index self-administered questionnaires. Stress, fatigue and quality of the relationship with partner were also measured using the PSS (Perceived Stress Scale), MFI-20 (Multidimensional Fatigue Inventory) and DAS (Dyadic Adjustment Scale) quality of life measures, respectively. There was a significant increase in free testosterone and E2 in the active group as well as sexual desire and arousal compared with the placebo group. The results indicate that this extract of T. foenum-graecum may be a useful treatment for increasing sexual arousal and desire in women. Copyright © 2015 John Wiley & Sons, Ltd.
http://www.researchgate.net/profile/Luis_Vitetta/publication/275354668_Influence_of_a_Specialized_Trigonella_foenum_graecum_Seed_Extract_%28Libifem%29_on_Testosterone_Estradiol_and_Sexual_Function_in_Healthy_Menstruating_Women_a_Randomised_Placebo_Controlled_Study/links/553ae3960cf2c415bb08fe6d.pdf?ev=pub_ext_doc_dl&origin=publication_list&inViewer=true

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Administration of T. foenum-graecum seed extract was also associated with a significant increase in E2 levels. Estradiol stimulates vaginal lubrication and blood flow, affecting a woman’s capacity for sexual arousal and orgasm (Simon, 2011); this supports the significant positive change in sexual arousal observed. Whilst the mechanism of the increase in E2 levels is unclear from the current study, one possibility is due to increased aromatase activity that converts testosterone to E2.