22-07-2012, 03:16 PM
(22-07-2012, 02:29 PM)Isabelle Wrote: Nobody has more experience with the effect of hops on total testosterone than you have
I'm not so sure about that .....
(22-07-2012, 02:29 PM)Isabelle Wrote: SHBG binds strongest to DHT, then testosterone, then estrogens.
Your order (DHT, testesterone, then estrogens) is what confuses me. This is how I understand it .....
Your body produces Testosterone (this is focused on Bio Males) .... that number is what is called when tested "Total Testosterone". Normal male testosterone level range given is 250 -1100 ng/dl ... but a level below even 400 will usually have signs.
SHBG and Albumin binds with Total Testosterone .... what remains behind is Free Testosterone and Bio-available Testosterone.
Here's a caclulator if you know your numbers
http://www.issam.ch/freetesto.htm
Normal range for Free T is 35.0-155.0 pg/mL.
Next 5 alpha reductase ... which is not as strong as SHBG/Albumin ... gets its shot at Free Testosterone .... it makes DHT. (lowering DHT leaves more Free T to make Estradiol)
Then poor ole aromatase get to grab it's chunk from what's left of Free T to make Estradiol ... (blocking aromatase tends to not allow you to make more DHT since the 5a reductase has already had it's turn)
I'm sure that there are other things going on but that's my understanding of the pecking order.
karen