12-07-2012, 11:20 AM
(12-07-2012, 10:24 AM)Isabelle Wrote: I'll get some more practice scoring free repairs, and then try a higher league
You get em girl ....
(12-07-2012, 10:24 AM)Isabelle Wrote: When you get the hops strobiles, manipulate them as little as possible. If they're whole, throw them in oat meal as they are, sweeten with honey and raisins, pour milk on it, and eat it like a porridge, microwaved if you prefer.
I have a real sensitive "grain scale" (1 grain = 64.79891 milligrams) I think I'm going to use it to start with so I can have real tight control over how much I take ... what do you suggest that I start with? Keep in mind I would use approx 1 1/2 times what you do based on body weight.
(12-07-2012, 10:24 AM)Isabelle Wrote: Off the top of my head, binding affinity of 8-PN is 20 times lower than that of estradiol. That's in the range where you want it, by the way, because you don't want your body's own estrogens replaced on the receptors by 8-PN. Looking at the numbers in the article you found, estrone will already be knocked out.
Do you have a fairly good grasp of how binding works? Things like once a receptor is bound how long does it stay bound? Can something with a stronger affinity come along and "bounce" the weaker off of the receptors OR does it have to wait until the weaker one "exhausts itself" and then replace it? I'd love to read some articles if you have any. I'm really getting fascinated learning about the whole endrocine system.
I also started reading about half-life of chemical compounds in the body. And they are all different. For example I found that Saw Palmetto has a 1/2 life of 19 hours .... so even after a 24 hour period there is a residual left that a new dose would "add" on top of ... forcing your SP level "overtime" through the roof. Wonder if that could happen to other components of NBE ... so that if there is any residual left in the system when the next dose is taken it would continually add to the amount in your system ... end result, overtime you would "stall" without ever increasing the amount you take every day.
Hugs to you ... Karen