01-12-2011, 08:13 PM
(This post was last modified: 01-12-2011, 08:15 PM by mochaccino.)
Isabelle, I just wanted to chime in to say you are awesome The cosupplementation study is especially interesting. It would take me forever to point out everything about that study that interests me, but the details they gave about the differences in "the in vitro microbial metabolism of isoflavones, prenylflavonoids, and lignans", are really shocking. I knew there were differences in the way individuals metabolize phytoestrogens, but I never realized the differences were so stark. This is just a highlight for anyone who is interested:
As expected, the in vitro microbial metabolism of isoflavones, prenylflavonoids, and lignans varied from 0 to 100% conversion of daidzein into equol (SOY incubations), IX into 8-PN (HOP incubations), and SECO into ENL (FLAX incubations). Consequently, participants were phenotyped as poor (n = 65, 68, and 34), moderate (n = 7, 14, and 21), and strong (n = 28, 18, and 45) in vitro equol, 8-PN, and ENL producers, respectively.
As expected, the in vitro microbial metabolism of isoflavones, prenylflavonoids, and lignans varied from 0 to 100% conversion of daidzein into equol (SOY incubations), IX into 8-PN (HOP incubations), and SECO into ENL (FLAX incubations). Consequently, participants were phenotyped as poor (n = 65, 68, and 34), moderate (n = 7, 14, and 21), and strong (n = 28, 18, and 45) in vitro equol, 8-PN, and ENL producers, respectively.