01-12-2011, 01:18 PM
I'm still wondering whether doses of soy milk should really be small. The same people who published the hops-flax-soy cosupplementation study
"Cosupplementation of isoflavones, prenylflavonoids, and lignans alters human exposure to phytoestrogen-derived 17β-estradiol equivalents"
http://jn.nutrition.org/content/139/12/2293.full
looked into safety of soy and hops:
Disposition of soy isoflavones in normal human breast tissue. "After intake of soy milk and soy supplements, isoflavones reach exposure levels in breast tissue at which potential health effects may occur."
http://www.ajcn.org/content/91/4/976.full
This was for 250 ml soy milk three times daily.
Disposition of hop prenylflavonoids in human breast tissue
http://onlinelibrary.wiley.com/doi/10.10...9/abstract
"Low doses of prenylflavonoids are unlikely to elicit estrogenic responses in breast tissue."
The low dose is three supplements daily for 5 days. The supplement was the same as in the hops-flax-soy cosupplementation study:
2.04 mg xanthohumol (XN), 1.20 mg isoxanthohumol (IX), and 0.1 mg 8-prenylnaringenin (8-PN) per supplement.
In my post # 661 at the top of this page, I linked a publication, reporting that hops pellets contain 0.62 g isoxanthohumol per 100 g. So 1.20 mg isoxanthohumol is 100 * 1.20/620 = 0.2 g hops pellets, or 200 mg, three times daily makes 600 mg.
From my own experience, I agree that 600 mg hops is too little for NBE. Using the same methods, the authors came to the conclusion that 750 ml soy milk is enough for "health effects" to occur. So if you want to start soy milk, don't drink a bottle every day
"Cosupplementation of isoflavones, prenylflavonoids, and lignans alters human exposure to phytoestrogen-derived 17β-estradiol equivalents"
http://jn.nutrition.org/content/139/12/2293.full
looked into safety of soy and hops:
Disposition of soy isoflavones in normal human breast tissue. "After intake of soy milk and soy supplements, isoflavones reach exposure levels in breast tissue at which potential health effects may occur."
http://www.ajcn.org/content/91/4/976.full
This was for 250 ml soy milk three times daily.
Disposition of hop prenylflavonoids in human breast tissue
http://onlinelibrary.wiley.com/doi/10.10...9/abstract
"Low doses of prenylflavonoids are unlikely to elicit estrogenic responses in breast tissue."
The low dose is three supplements daily for 5 days. The supplement was the same as in the hops-flax-soy cosupplementation study:
2.04 mg xanthohumol (XN), 1.20 mg isoxanthohumol (IX), and 0.1 mg 8-prenylnaringenin (8-PN) per supplement.
In my post # 661 at the top of this page, I linked a publication, reporting that hops pellets contain 0.62 g isoxanthohumol per 100 g. So 1.20 mg isoxanthohumol is 100 * 1.20/620 = 0.2 g hops pellets, or 200 mg, three times daily makes 600 mg.
From my own experience, I agree that 600 mg hops is too little for NBE. Using the same methods, the authors came to the conclusion that 750 ml soy milk is enough for "health effects" to occur. So if you want to start soy milk, don't drink a bottle every day