[Lotus]

Hi Sweets, 

Apologies for the late response, we have a lot in common lol. I've taken mirtazapine for a sleep disorder too and had the same issue waking up the next morning and weight gain. I was recommended to try Trazodone which is similar to mirtazapine, some say the side effects are the same, in my case I didn't get the mirtazapine hangover and hunger from hell, the change really helped me though, talk to your doctor…see what they think. ? Have you tried melatonin to help fall asleep? 

But seeing you describe depression, anxiety, trouble sleeping and having pcos makes me suspect cortisol related issues mixed with pcos. Turns out androgens, insulin, cortisol play havoc on pcos. High cortisol levels can mimic pcos symptoms too. Don't let the title of the science article throw off, of you read the entire article the talk about lean subjects versus obese subjects, so there's differences to productions rates and metabolic rates. The main point being is how cortisol could be the main culprit behind your pcos, ance, sleep disturbance, weight gain, fatigue, etc...this of course is just my observation, fwiw.

 
Altered cortisol metabolism in polycystic ovary syndrome: insulin enhances 5alpha-reduction but not the elevated adrenal steroid production rates
"The changes in 5alpha-R, 11beta-HSD1, and 20alpha/beta-HSD enzyme activities observed in PCOS may contribute to the increased production rates of cortisol and androgens, supporting the concept of a widespread dysregulation of steroid metabolism." 
https://pubmed.ncbi.nlm.nih.gov/14671189/