15-08-2020, 08:03 AM
(12-08-2020, 04:12 PM)sweetorange Wrote:PS: (very important one)
Ellen (MissMadScientist) had a huge success with her BO program not just because BO - she was taking BCP, BO, ibutamoren and TAGAMET. Last week I realised thats the med my mom uses for gastric acid issues and my mind *blew up* in the moment.
This question is for Lotus: did she touch every-single-botton (estrogen+antiandrogen+growth hormone) for her huge growth? " alt="" title="">
Hard to say, I never actually saw a photo to confirm said growth. For breast growth estrogen, progesterone, growth hormone (GH), insulin-like growth factor 1 (IGF-1), and prolactin need to be present. Back in the day people (Tibetan, Jennifer, Bonita, Cece, Ella, and others) actually posted photos so folks could correlate growth towards developing their own programs. Some shared photos wearing a bra while others didn't...I don't doubt growth occurred, I just never saw it. Look, don't get me wrong, Miss Ellen is a nice person, so nuff said.
Taking MK-677 carries risks. See there's a chance taking IGF-1 elevates breast hyperplasia and cancer. In luteal phase IGF-1 is naturally produced, people don't talk about this though. IGF-1 locally in the breast were doubled in the luteal, when estradiol and progesterone levels were elevated, compared with the follicular phase.
So like I said, I'd rather see cis-females get IGF-1 naturally as opposed to supplementing with IGF-1. Just inhibit somatostatin and stimulate pituitary GH and you'll see IGF-1 come around.
Increase of Free Insulin-Like Growth Factor-1 in Normal Human Breast in vivo Late in the Menstrual Cycle
The results showed that the extracellular levels of free IGF-1 locally in the breast were doubled in the luteal phase, when estradiol and progesterone levels were elevated, compared with the follicular phase. In plasma, free IGF-1 levels also exhibited a cyclic variation but to a lesser extent. The increased local levels of the free form of IGF-1 may promote proliferation in the breast epithelium. This could be important in sex steroid dependent breast cancer development.
https://link.springer.com/article/10.102...4575103524
The role of the insulin-like growth factor-1 system in breast cancer
Although many of the relevant molecular pathways and intracellular cascades remain to be elucidated, a growing body of evidence points to the important role of the IGF-1 system in breast cancer development, progression and metastasis
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4335664/
Growth Hormone and Insulin-Like Growth Factor-I in the Transition from Normal Mammary Development to Preneoplastic Mammary Lesions
For example, systemic administration of GH or IGF-I causes mammary hyperplasia, and overproduction of IGF-I in transgenic animals can cause the development of usual or atypical hyperplasias and sometimes carcinoma.
https://www.ncbi.nlm.nih.gov/pmc/article...po=63.1915