(10-09-2014, 06:56 AM)Candace Wrote: I looked into the other things on the anti-prolactin list and think that licorice, goldenseal, ginger, and vitamin B6 should also be removed.
Vitamin B6 is unreliable[/url], and the effective dose (200-600 mg) is in the toxic range. (The upper limit for B6 is 100 mg.)
Who's suggesting taking the upper limit's?, the research is clearly out there.
Certain medications interfere with the metabolism of vitamin B6; therefore, some individuals may be vulnerable to a vitamin B6 deficiency if supplemental vitamin B6 is not taken. In the NHANES 2003-2004 analysis, significantly more current and past users of oral contraceptives (OCs) among menstruating women had low plasma PLP levels compared to women who have never used OCs, suggesting that the estrogen content of OCs may interfere with vitamin B6 metabolism (see Side effects of oral contraceptives below) (88). Anti-tuberculosis medications (e.g., isoniazid and cycloserine), the metal chelator penicillamine, and anti-parkinsonian drugs like L-Dopa can all form complexes with vitamin B6 and limit its bioavailability, thus creating a functional deficiency. PLP bioavailability may also be reduced by methylxanthines, such as theophylline used to treat certain respiratory conditions (7). The long-term use of nonsteroidal anti-inflammatory drugs (NSAIDs; e.g. celecoxib and naproxen) may also impair vitamin B6 metabolism (91). Conversely, high doses of vitamin B6 have been found to decrease the efficacy of two anticonvulsants, phenobarbital and phenytoin, and of L-Dopa. (6, 90).
http://lpi.oregonstate.edu/infocenter/vitami
Influence of administration of pyridoxine on circadian rhythm of plasma ACTH, cortisol prolactin and somatotropin in normal subjects].
http://www.ncbi.nlm.nih.gov/pubmed/?term=6324828
Effect of clonidine on growth hormone, prolactin, luteinizing hormone, follicle-stimulating hormone, and thyroid-stimulating hormone in the serum of normal men.
http://www.ncbi.nlm.nih.gov/pubmed/1184719
Pyridoxine (B6) suppresses the rise in prolactin and increases the rise in growth hormone induced by exercise.
http://www.ncbi.nlm.nih.gov/pubmed/7088124
Influence of administration of pyridoxine on circadian rhythm of plasma ACTH, cortisol prolactin and somatotropin in normal subjects].
http://www.ncbi.nlm.nih.gov/pubmed/6324828
Nutritionally relevant supplementation of vitamin B6 in lactating women: effect on plasma prolactin.
http://www.ncbi.nlm.nih.gov/pubmed/4058985
Effect of pyridoxine on plasma levels of HGH, PRL, and TSH in normal women
http://www.ncbi.nlm.nih.gov/pubmed/358720
Pyridoxal phosphate inhibits pituitary cell proliferation and hormone secretion.
http://www.ncbi.nlm.nih.gov/pubmed/16690808