[HopefulKitKat]

We need the liver to activate the CYP P450 enzyme system (which account for about 3/4 of drug metabolism). However, transdermal application accounts for 60% absorption, but....oral delivery effectiveness is only 15 to 20%. So, from my experience utilizing 3 methods (including sublingual) work together.
 

I meant to ask about sublingual application... Would it be possible to with something that's not a liquid? Like, could I bust up my PM capsules and spread the powdery contents under my tongue for a while? Could the properties somehow absorb there if I leave it for long enough, about half an hour or so? It'd be very hard not to swallow for that long though for me, especially in the mornings.
Once enough time passes and I think my tongue absorbed enough, should I just swallow it all anyway or spit it out? I guess I should spit it out since that's the whole point to avoid the liver, but I'm such a cheapskate!

General averages of rates/ratios when consuming herbs

Q-How long does a capsule take to dissolve?

A-Typically the average is up to 20 minutes, some sources have at 5-10 minutes while others say 20-30 minutes. Extracts 1 to 4 minutes

Q-What are typical absorption results?

A-For skin application- 60%

A-Liquid- 98%

A-capsule- 10-20%

Q-What is the capsule to extract ratio?

A-20 to 1, meaning it would take 20 capsules to = 1 teaspoon of extract


Q-When is the best time to take an herb?

A-In general herbs are best taken on an empty stomach

 

Lots of things inhibits growth, like low blood glucose, diabetes, drug interaction, digestion issues, pH balance is off, unsafe products... etc, etc. On top of that, some people lack certain genes to code enzymes to be metabolized properly. But ultimately I think one has to reset the body's immune system when taking on NBE, and what I mean by that is detoxifying the whole body, not just the liver, (fasting is my preferred method for a reset).

Oh man, fasting is so hard! Could I like, do an apple fast maybe? Where all I eat is apples for some time. I tried it once but I think I couldn't help but give up! Maybe if I eat a combination of veggies and fruits I can stick with it much better, more so as a general cleanse away from junky food...
 

do mean taking anti-androgens (too inhibit DHT) while taking testosterone?.... taking this approach I think ultimately boost aromatase.

Ack, I meant inhibiting both DHT and/or testosterone, but now my head's getting all jumbled, haha! But good to know!
I've been looking for a good DHT inhibitor and read many of your posts, but am still undecided on which to go for. So far I'm leaning towards Red Reishi...
I don't want to mess with testosterone at all, taking Saw Palmetto didn't sit well with me.

 

You also have to consider what brain signaling has to do with the pituitary gland and GH, and this gets equally complicated as the brain (even the hypothalamus) has estrogen receptors, as do target tissues, (even the bones). As the body has about a trillion cells, a estrogen receptor (as an example) has hundreds of thousands receptor sites....however, not all go through (or make it to synthesize for transcription...aka DNA). So you can see there's lots of things that stand in the way to breast growth.

Check out this site below.... (and the other link I provided on citicholine). I do think we can overcome oral E inhibiting IGF-1.
 http://www.lifeextension.com/magazine/20...ly/Page-01

The bottom line is trying to balance all the essential parts for breast growth, which means all the hormones (including GH), including diet and some form of exercise helps w/growing breasts. Avoid stress as best one can (stress trigges cortisol which can derail growth much like DHT does).



L.

My biggest struggles since childhood are getting decent nutrition and most of all consistently adequate sleep... I was always a picky eater, so even though I don't eat burgers or Thanksgiving dinner, the few foods I do eat mostly aren't the best. I gave up soda, punch, and juice for only water when I first started getting acne, and even slowly fazed out snacks and desserts over the years (except sometimes chocolate Reese's yumm!!!), and recently started to eat more kale and broccoli/cauliflower along with actually cooking real meals for myself more often... But I still got a long way to go.
As for sleep... Sometimes I feel lack of sleep is what ultimately plagued me with acne all these years, and now that I think about it probably stunted my boobs too. I can't think of the last time I consistently fell asleep at a good time through the entire week let alone month... Probably before I was 10.

Anyway, I'll pick back up with exercise this week since I fell off for the past couple weeks, and continue on my never-ending quest to go to bed when I should. :'D

Thank you again, Lotus!

(Also, sweetorange, reading your post is making me kick myself since I just gave my MSM away!)