(07-04-2013, 03:59)mochaccino Wrote: For some reason I thought that cell proliferation was what they always look for to determine if any substance is estrogenic. Is that wrong? Is it more complicated than that? I should do more research into how scientists determine if something is estrogenic. If anyone already knows, can you explain please?
Not entirely... That's part of it, yes, but the much bigger part is its activity on estrogen receptors. Which that aspect trig appears to have none of. It's only when paired with E2 that it's estrogenic. Meaning it ONLY increases cell proliferation, but is itself not binding to the receptor.
Or at least, that's the way I'm reading that article. I suppose I could be missing something.
EDIT: Though this does mean that my original knowledge regarding that chemical was erroneous, and I'm willing to admit that. I'm always learning new things. It still doesn't do anything that'd interfere with real phytoestrogens though, in fact, this only further reinforces the idea that FG actually pairs well with phytoestrogen.