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Help Understanding Hormone Results
#13

(25-01-2023, 03:21)surferjoe2007 Wrote:  Oh interesting, I just went with one of the options you mentioned.  Do you have a link to what it should be for day 4?  Or did you mean to say that her DHEA-S is too low rather than too high?

It doesn't make a difference now because the calculation was off, in fact it was low. The point is minimango spelled out her mood swings, hair loss, stress and fatigue...which are signs of adrenal fatigue, there's a slim chance of PCOS and even possibly Lupus. I'm trying to help her here, are you? There's a reason why labs are tested on certain days (e.g. day 3-4)...you should spend researching that.
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Minimango, 

I'm offering a hypothetical on why it is still possible to have link to PCOS (albeit slim). Some women who have pcos don't even know it. In the literature below they describe where DHEA-S is actually lowered overtime. Read the study, it's quite interesting because it describes some of the symptoms you point out and describe…remember I'm just offering a hypothesis. 

DHEA and polycystic ovarian syndrome: Meta-analysis of case-control studies
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8691613/

PCOS women tend to suffer from psychological symptoms of mood swings, depression and anxiety, I'm listing a few of the highlights from the Meta-analysis. Some fit some don't.

It is known that acute psychosocial stress increases cortisol release in response to ACTH. As, dehydroepiandrosterone (DHEA) and its sulphated form (DHEA-S) are also released from adrenals in response to ACTH, it is quite logical to regard that the DHEA is also increased in response to acute stress [11]. However, long term psychosocial stress causes a decline in the levels of DHEA and its sulphated form, as it plays a role in resilience and successful adaptation to extreme stress [12].

30 studies were qualified for meta-analysis. Three studies were further separated as they had more than one case-control groups. Therefore, the total number of final studies included was 33 articles.

PCOS women with infertility tend to be more anxious and this often sparks into a vicious cycle where increased anxiety and stress worsens infertility and vice-versa. Moreover, these women tend to adopt unhealthy eating behaviours and sedentary lifestyle so as to cope up with the psychological distress and emotional trauma
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