13-08-2016, 20:41
It's the 2/16 alpha-hydroxyestrone pathway that has roughly a 30% increase in breast cancer. Shifting Estradiol into a safer pathway (end metabolites) of 2OHE1 is safer, (w/Indole-3-Carbinol & DIM etc) increase 2OHE1 urinary excretion (that's good a thing).