28-04-2016, 04:08
That's interesting. So two other compounds have been isolated in reishi that have a strong 5ar-inhibitory activity. So it'd combine well with a more competitive estrogen that is also stronger than the estrogenic compound in reishi and with something with a stronger source of coumarin to help block the total testosterone as well for someone with REALLY high testosterone of both types (like me) and EGCg to help convert whatever's left to E.
Unless someone actually manages to combine reishi and BO and the estrogenic compound in reishi does not interfere with the BO, then I'm still going to have to hold that it is unlikely to combine well with BO, however. Which has been a frequent question of late. With PM, clearly it works out without the reishi compromising the (deoxy)miroestrol.
I'll give it a try adding it to my GTE routine next month as it is fairly inexpensive and if it works it should raise effectiveness of GTE towards NBE, though I'll probably still need to add tonka bean eventually to really block my testosterone sufficiently as well as a replacement estrogen.
And no, coumarin is not a 5AR inhibitor, it's a 17,20 lyase inhibitor IIRC, I do remember it's higher up the chain at least, but I could be confusing exactly where without looking it up again. It inhibits TESTOSTERONE production, not the reduction of testosterone to DHT. It has similar efficacy though, but on total T, not DHT.
Unless someone actually manages to combine reishi and BO and the estrogenic compound in reishi does not interfere with the BO, then I'm still going to have to hold that it is unlikely to combine well with BO, however. Which has been a frequent question of late. With PM, clearly it works out without the reishi compromising the (deoxy)miroestrol.
I'll give it a try adding it to my GTE routine next month as it is fairly inexpensive and if it works it should raise effectiveness of GTE towards NBE, though I'll probably still need to add tonka bean eventually to really block my testosterone sufficiently as well as a replacement estrogen.
And no, coumarin is not a 5AR inhibitor, it's a 17,20 lyase inhibitor IIRC, I do remember it's higher up the chain at least, but I could be confusing exactly where without looking it up again. It inhibits TESTOSTERONE production, not the reduction of testosterone to DHT. It has similar efficacy though, but on total T, not DHT.