24-07-2015, 21:36
Since both IGF-1 and vitamin D are expressed throughout the body and have a broad spectrum of effects, the interplay between the two hormones is complex.
A positive correlation between serum concentrations of IGF-1, 25(OH)D and 1,25(OH)2D has been "repeatedly demonstrated" in healthy patients, the researchers wrote, adding that evidence indicates the association is at least in part causal.
Specifically, vitamin D has been shown to increase circulating IGF-1 and IGF binding proteins (IGFBP-3), while administration of growth hormone and IGF-1has been shown to increase vitamin D levels in several studies, they reported.
http://www.medpagetoday.com/Endocrinology/GeneralEndocrinology/40932
A positive correlation between serum concentrations of IGF-1, 25(OH)D and 1,25(OH)2D has been "repeatedly demonstrated" in healthy patients, the researchers wrote, adding that evidence indicates the association is at least in part causal.
Specifically, vitamin D has been shown to increase circulating IGF-1 and IGF binding proteins (IGFBP-3), while administration of growth hormone and IGF-1has been shown to increase vitamin D levels in several studies, they reported.
http://www.medpagetoday.com/Endocrinology/GeneralEndocrinology/40932