10-11-2014, 04:13
(09-11-2014, 12:53)Koko Wrote: Hi lotus.
This has been really helpful thread. I just want to ask about green tea to make my understanding clearer.
It has anti-androgenic effects but also anti-estrogenic? Is that right?
Yes, it ties up estrogen and testosterone by way of SHBG, reducing each.
Sex hormone-binding globulin (SHBG) or sex steroid-binding globulin (SSBG) is a glycoprotein that binds to the sex hormones, androgen and estrogen. Other steroid hormones such as progesterone, cortisol, and other corticosteroids are bound by transcortin.
It's also reported to inhibit aromatase , (*albeit rat study). It seems there's plenty of misinformation out there too.
(We also found that P-60 as a whole and some of its constituents exhibited inhibitory effects on human placental aromatase activity by in vitro assay.)
http://www.ncbi.nlm.nih.gov/pubmed/12065214