17-07-2014, 00:40
(16-07-2014, 23:05)lovely11 Wrote: estrogen doesn't increase serum prolactin, it lowers it. Estrogen increases prolactin Receptor sensitivity. Meaning the receptor responds more to less estrogen.
During pregnancy, high circulating concentrations of estrogen increase prolactin levels by 10- to 20-fold.
On another note:
Excessive estrogen in circumstances of deficient progesterone induces a decrease in receptor sensitivity. One of progesterone's functions is to restore the normal sensitivity of estrogen receptors. When progesterone is restored, estrogen receptor sensitivity is restored also.