[Dynsei]

Prolactin can be problematic with aromatase,

Aromatase activity is decreased by prolactin, anti-Müllerian hormone and the common herbicide glyphosate. Aromatase activity appears to be enhanced in certain estrogen-dependent local tissue next to breast tissue, endometrial cancer, endometriosis, and uterine fibroids.
http://wikipedia.org/wiki/Aromatase

Prolactin synthesis in primary cultures of pituitary cells: Regulation by estradiol

Evidence That Autoregulation of Prolactin Production Does Not Occur at the Pituitary Level
http://press.endocrine.org/doi/abs/10.1210/endo-110-3-722

Prolactin and progesterone are compatible with each other, but both lower and are lowered by estrogen. This supports that about aromatase. Prolactin and progesterone are also responsible for growth. Aromatase is always good for reducing androgens. Prolactin and progesterone which can work together are as important as estrogen each. During the cycle, the results were that prolactin and igf-1 were the major factor during follicular phase. The text also showed that BCP (which is both estrogen and progesterone, and some bcps are prolactins) had a positive effect with prolactin.

Even though progesterone and estrogen do fight each other's effects, during the luteal phase, phyto supplementation also intensifies each others effects on breasts even more. The first link on this thread saying, progesterone being at its highest, followed by estrogen being high showed positive effects.

From the showing that estrogen, progesterone, and prolactin all present at higher than the amounts they normally are during 1 time period showed positive effects.Then the showing that progesterone at its highest when it normally peaks, during luteal with high for that time, but not peak, estrogens.

Prolactin generally doesn't follow the menstrual cycle. It can be caused by physical and mental conditions, and is usually highest after waking up. If it not following a cycle is why it is not considered autoregulation, this could be why. I agree with estrogen that is on a cycle influences prolactin, but it also operates on a daily instead of monthly basis.

Either way, the three hormone groups (prolactin, progestogens, estrogens) have to be cycled or possibly they can all work together at once, but at different ratios for different times. Upregulation is another reason to use all three hormones; the hormone will upregulate the other two respective receptors while downregulating its own. Perhaps certain specific hormones of the three groups should be used, because there are many types of progestogens, estrogens and the phytohormones with effects we don't know about.