31-03-2010, 02:33
Accidental_booby, phytoestrogens do not need to be metabolized to work. It doesn't work by being converted into human hormones, it acts like the estrogen without being broken down.
Think of this analogy;
You have a lock (estrogen receptor), and it only opens with a heart shaped key (estrogen). Another key (phytoestrogen) is shaped like a circle, but is so similar to the other key, that it unlocks the same lock. This way, you can activate these estrogen receptors using fake estrogen (phytoestrogens). They are not metabolized. So the information you have, even though accurate, does not change the effectiveness of wild yam. It is irrelevant.
Think of this analogy;
You have a lock (estrogen receptor), and it only opens with a heart shaped key (estrogen). Another key (phytoestrogen) is shaped like a circle, but is so similar to the other key, that it unlocks the same lock. This way, you can activate these estrogen receptors using fake estrogen (phytoestrogens). They are not metabolized. So the information you have, even though accurate, does not change the effectiveness of wild yam. It is irrelevant.