04-10-2014, 06:55
(04-10-2014, 03:52)pom19 Wrote: Well, I did not mention that I was actually one of those who did get side effect from Nature's answer PM. I found out after finding out that it has about 8333% of RDA of B12 which is about 83 times!!! I developed skin rashes, and after a week of stopping it it all disappeared. It really was scary, since I am very healthy and have always had a good and clear skin, even during my puberty. So, it was tough to see for the first time in my life to have such rashes. I had some hives in past as a result of food allergy, but nothing like that. Oh, well, it apparently does not happen to everyone. Again, I have a very sensitive body and skin, of course on the good side though.
The B12 RDA (2.4 mcg) is 50% absorbed, while 500 mcg is 0.5% absorbed, so the effective difference is (500 * 0.005)/(2.4 * 0.5) = just a factor of 2, not 83. (That 83 assumes an RDA of 6 mcg, which is a common error that the more clueless supplement companies make.) Furthermore, B12's half-life in the body is a year or more, so a week wouldn't have been long enough to clear it. I think you were probably reacting to the DIM. Google diindolylmethane and rash to see what I mean.