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Changing your sex changes your brain: influences of testosterone and estrogen on adult human brain structure.

Objective: Sex hormones are not only involved in the formation of reproductive organs, but also induce sexually-dimorphic brain development and organization. Cross-sex hormone administration to transsexuals provides a unique possibility to study the effects of sex steroids on brain morphology in young adulthood.

Methods: Magnetic resonance brain images were made prior to, and during, cross-sex hormone treatment to study the influence of anti-androgen + estrogen treatment on brain morphology in eight young adult male-to-female transsexual human subjects and of androgen treatment in six female-to-male transsexuals.

Results: Compared with controls, anti-androgen + estrogen treatment decreased brain volumes of male-to-female subjects towards female proportions, while androgen treatment in female-to-male subjects increased total brain and hypothalamus volumes towards male proportions.

Conclusions: The findings suggest that, throughout life, gonadal hormones remain essential for maintaining aspects of sex-specific differences in the human brain.

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Hi Denita,

Nice job, so basically the brain for each sex has a comparable opposite structural volume change, interesting!
(27-04-2014, 11:46 PM)Lotus Wrote: [ -> ]Hi Denita,

Nice job, so basically the brain for each sex has a comparable opposite structural volume change, interesting!

Yes very interesting. Effectively it proves brain rewiring!
i had read somewhere that the hypothalimus is primarily responsible for gender. if i recall right, females have a larger hypothalamus than males. it was also found that transexuals/mtf had larger hypothalamus than genetic males.it was not able to be determined if this was from hormone use or naturally enlarged. due to its location deep in the brain, one can not examine it unless it is through autopsy.

there is still too little research in regards to the hypothalamus and its relation in regards to gender dysphoria

about the hypothalamus :http://en.wikipedia.org/wiki/Hypothalmus

read whole page
that is so strange that physical neuronal changes can occur in a mature brain due to shifting hormonal influences. this may be a really stupid question, i'm always reading here or there about phytoestrogens in this food or herb or spice but i don't think i've ever heard the term phytoandrogen. do those even occur. if so, maybe, it would explain some few differences in cultural perspectives and attitudes, you know, more aggressive, warlike or spiritual, cooperative. if so, that would mean diet rules. btw, just for the record, women are superior beings. Tongue
(27-04-2014, 11:32 PM)Denita Wrote: [ -> ]Changing your sex changes your brain: influences of testosterone and estrogen on adult human brain structure.

Objective: Sex hormones are not only involved in the formation of reproductive organs, but also induce sexually-dimorphic brain development and organization. Cross-sex hormone administration to transsexuals provides a unique possibility to study the effects of sex steroids on brain morphology in young adulthood.

Methods: Magnetic resonance brain images were made prior to, and during, cross-sex hormone treatment to study the influence of anti-androgen + estrogen treatment on brain morphology in eight young adult male-to-female transsexual human subjects and of androgen treatment in six female-to-male transsexuals.

Results: Compared with controls, anti-androgen + estrogen treatment decreased brain volumes of male-to-female subjects towards female proportions, while androgen treatment in female-to-male subjects increased total brain and hypothalamus volumes towards male proportions.

Conclusions: The findings suggest that, throughout life, gonadal hormones remain essential for maintaining aspects of sex-specific differences in the human brain.

_________________________________
Source:
Full text.
Full pdf
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Very interestig!!! I like this. Thanks for posting this. <3 POM